Research & Development

At BrainPlotting, we offer the best tools and technologies to deliver the finest predictions. They result from more than 15 years of research and development conducted in several academics as well as private companies.

We excel in brain Human cell cultures for more than 5 years now and we continually innovate and characterize new models, in our lab and in collaboration with laboratories of excellence.

Partnership with Paris Descartes University

We characterize specific transporters on the Human blood brain barrier with the team of Dr Cisternino and Pr Declèves. For that, we use validation tools in immunology and functionality tests as well as recent transcriptomic and proteomic approaches.

• Cannabidiol Increases Proliferation, Migration, Tubulogenesis, and Integrity of Human Brain Endothelial Cells through TRPV2 Activation. Luo et al 2019
• Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells. Luo et al 2019

Partnership with Institut Cochin

With the team of Dr Bourdoulous, we study the mechanisms of infection by the Neisseria meningitidis bacteria, a pathogen known to specifically target the human BBB.

Partnership with Servier technology 

With Servier Technology, we validate the presence and the functionality of efflux transporters on our BBB model by the passage of known drugs possessing different characteristics. This partnership allow us to validate our models for screening projets by pharmaceutical industrials.

Scientific Poster at SEISC Meeting 2018